Researchers from WorldCare Consortium™ member Dana-Farber Cancer Institute have found how thalidomide produced such severe fetal harm in thousands of children whose mothers took it while pregnant. The discovery not only answers a mysterious question that has been the subject of scientific curiosity for two...
The diagnosis of diseases based in internal organs frequently relies on biopsy samples from the affected regions, but collecting such samples is often error-prone due to the fact that current endoscopic imaging techniques are unable to accurately visualize disease sites. Conventional optical elements in catheters...
A new study from WorldCare Consortium™ member Boston Children’s Hospital provides insight into why non-damaged portions of spinal cord frequently don’t permit movement below the actual site of spinal cord injury in patients. In addition, the study shows that injection with a small-molecule compound can...
A new study led by investigators at WorldCare Consortium™ member Brigham and Women’s Hospital has found that checkpoint blockade immunotherapies provide significant improvements in overall survival for patients with melanoma brain metastases. The researchers were able to gather a large enough dataset to determine the effectiveness...
Researchers at WorldCare Consortium™ member McLean Hospital have completed a study that aimed to determine which individuals with depression are best suited for antidepressant medications. Their findings have led to the development of a statistical algorithm identifying patients who may best respond to antidepressants, before...
Normally, scar tissue forms to heal an internal wound and then quietly retreats once the wound is healed, but in many common diseases, such as kidney, liver and lung fibrosis, the scar tissue strangles vital organs. These diseases are widely untreatable and ultimately fatal. Fibrosis,...
Research from WorldCare Consortium™ member Mayo Clinic has found that by using compounds to kill senescent cells, which have become dysfunctional due to aging yet do not actually die, scientists were able to increase the lifespan and “healthspan” of mice, suggesting that biological renovation and rejuvenation...
A study from WorldCare Consortium™ member UCLA Health has found that parents who have had severe stresses and trauma in their childhood are more likely to have kids with behavioral health problems. The types of childhood hardships these parents had included separation or divorce of...
WorldCare Consortium™ members Massachusetts General Hospital and Brigham and Women’s Hospital will apply deep learning, a type of machine learning based on data representations, to medical records and images to automate the things that humans do well, but don’t want to do or don’t have...
Ben Smith, a 25-year-old resident of New South Wales, Australia, was concerned about a hard lump on his left testicle in December of 2017, when his general practitioner told him that the swelling and pain was probably just hormonal and that the lump did not...