Scientists at WorldCare Consortium™ member Dana-Farber Cancer Institute discover how thalidomide produced birth defects

08:00 06 August in Health, Medicine
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Researchers from WorldCare Consortium™ member Dana-Farber Cancer Institute have found how thalidomide produced such severe fetal harm in thousands of children whose mothers took it while pregnant. The discovery not only answers a mysterious question that has been the subject of scientific curiosity for two...

Researchers at WorldCare Consortium™ member Massachusetts General Hospital team up with Harvard John A. Paulson School of Engineering and Applied Sciences to develop nano-optic endoscopes

08:00 01 August in Health, Medicine
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The diagnosis of diseases based in internal organs frequently relies on biopsy samples from the affected regions, but collecting such samples is often error-prone due to the fact that current endoscopic imaging techniques are unable to accurately visualize disease sites. Conventional optical elements in catheters...

Research from WorldCare Consortium™ member Boston Children’s Hospital shows insight and promise for treatment of paralyzing spinal cord injuries

08:00 30 July in Medicine
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A new study from WorldCare Consortium™ member Boston Children’s Hospital provides insight into why non-damaged portions of spinal cord frequently don’t permit movement below the actual site of spinal cord injury in patients. In addition, the study shows that injection with a small-molecule compound can...

New study by investigators at WorldCare Consortium™ member Brigham and Women’s Hospital finds immunotherapy doubles survival rates for patients with melanoma brain metastases

08:00 25 July in Health, Medicine
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A new study led by investigators at WorldCare Consortium™ member Brigham and Women’s Hospital has found that checkpoint blockade immunotherapies provide significant improvements in overall survival for patients with melanoma brain metastases. The researchers were able to gather a large enough dataset to determine the effectiveness...

Research study from WorldCare Consortium™ member McLean Hospital leads to development of algorithm that identifies patients best suited for antidepressants, before they begin treatment

08:00 23 July in Health, Medicine
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Researchers at WorldCare Consortium™ member McLean Hospital have completed a study that aimed to determine which individuals with depression are best suited for antidepressant medications. Their findings have led to the development of a statistical algorithm identifying patients who may best respond to antidepressants, before...

New study from WorldCare Consortium™ member Northwestern Medicine identifies a trigger of some fibrotic diseases and an experimental compound to treat it

08:00 18 July in Health, Medicine
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Normally, scar tissue forms to heal an internal wound and then quietly retreats once the wound is healed, but in many common diseases, such as kidney, liver and lung fibrosis, the scar tissue strangles vital organs. These diseases are widely untreatable and ultimately fatal. Fibrosis,...

Research from WorldCare Consortium™ member Mayo Clinic has found that senolytics improve physical function and increase lifespan in old age

08:00 16 July in Health, Medicine
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Research from WorldCare Consortium™ member Mayo Clinic has found that by using compounds to kill senescent cells, which have become dysfunctional due to aging yet do not actually die, scientists were able to increase the lifespan and “healthspan” of mice, suggesting that biological renovation and rejuvenation...

Study from WorldCare Consortium™ member UCLA Health finds that severe childhood trauma and stresses early in parents’ lives linked to higher rates of behavioral health problems in children

08:00 11 July in Health, Medicine
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A study from WorldCare Consortium™ member UCLA Health has found that parents who have had severe stresses and trauma in their childhood are more likely to have kids with behavioral health problems. The types of childhood hardships these parents had included separation or divorce of...

WorldCare Consortium™ members Massachusetts General Hospital and Brigham and Women’s Hospital to apply deep learning to medical records and images

08:00 09 July in Health, Medicine
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WorldCare Consortium™ members Massachusetts General Hospital and Brigham and Women’s Hospital will apply deep learning, a type of machine learning based on data representations, to medical records and images to automate the things that humans do well, but don’t want to do or don’t have...